Careers

At Leveragen, we aim to develop innovative solutions to challenging medical problems afflicting humans. We welcome professionals with diverse backgrounds, talents and skills to join us in our mission. The current job postings are listed below.

Salary will be commensurate with education and experience. Excellent benefits are provided, including stock options, bonuses, 401(K) plan, health and dental insurance, as well as work visa sponsorship. Leveragen is an equal opportunity, equal access, and affirmative action employer. If you are interested in joining us, please send us your resume and cover letter to careers@leveragen.com.

Research Scientist/ Senior Scientist/Principal Scientist – Molecular Geneticist

Job Description

We are currently seeking a highly motivated and talented molecular geneticist to support our genetic engineering team. The primary job responsibilities include:

Design genetic models for R&D and external collaborative projects
Engineer plasmid and BAC constructs, ES cell lines, and mouse embryos with various genetic manipulation technologies
Screen and validate genetically engineered ES cells and mice
Supervise genotyping and maintenance of mouse colonies
Write and update animal experimental protocols under IACUC guidance
Assist with mouse importation and exportation
Collect data, perform quality control, monitor data accuracy, document data within agreed upon timelines with supervisor, and present data in group meetings
Contribute to writing of documents, SOPs, safety standards, maintenance instructions and procedure manuals for laboratory equipment
Contribute to procedure optimization and technical development

The successful candidate must be able to manage time effectively to execute multiple concurrent projects, anticipate and troubleshoot technical problems, seek guidance when necessary, and work both independently and as part of a team with minimal supervision.

Qualifications

PhD in biological sciences with strong wet lab experience in mouse genetics
Demonstrated expertise in routine molecular biology techniques
Mastery of genetic engineering techniques including CRISPR and RMCE
Experience with BAC recombineering - a plus
Excellent attention to detail, organizational and communication skills

Research Associate, Genetic Engineering

Job Description

We are currently seeking a highly motivated and talented Research Associate to conduct molecular cloning and cell culture work to support the generation of engineered cell lines and genetically modified mice. The primary job responsibilities include:

Construction and preparation of plasmid and BAC vectors
Mammalian cell culture, transfection, and maintenance
Screening/genotyping engineered cell lines and mice
Collect data, perform quality control, monitor data accuracy, document data within agreed upon timelines with supervisor, and present data in group meetings
Read, understand, and interpret documents, SOPs, safety standards, maintenance instructions and procedure manuals for laboratory equipment
Contribute to procedure optimization and technical development

Qualifications

BS or MS degree in biological sciences or related fields
Demonstrated expertise in routine molecular biology techniques including DNA/RNA preps, bacteria transformation, agarose gel electrophoresis, cloning and PCR
Demonstrated expertise in mammalian cell culture and aseptic techniques
Experience with mouse handling is a plus
Excellent attention to detail, organizational and communication skills

Research Scientist/ Senior Scientist/Principal Scientist – NGS Technologist

Job Description

We are currently seeking a highly motivated and talented Research Technologist to support our internal R&D using next-generation sequencing (NGS) on Illumina and PacBio platforms. The primary job responsibilities include:

Prepare DNA and RNA samples suitable for NGS analysis
Design and implement protocols to successfully complete a variety of NGS workflows from library preparation to sequencing
Perform NGS data analysis with standard bioinformatic tools
Collect data, perform quality control, monitor data accuracy, document data within agreed upon timelines with supervisor, and present data in group meetings
Contribute to writing of documents, SOPs, safety standards, maintenance instructions and procedure manuals for laboratory equipment
Contribute to procedure optimization and technical development

Qualifications

PhD with strong wet lab and NGS experience
Demonstrated mastery in routine molecular biology techniques
Experience with preparing NGS libraries and executing NGS workflows
Competence with usage of standard bioinformatic tools for NGS analysis
Coding ability (i.e., R, Python, Perl) - a plus
Excellent attention to detail, organizational and communication skills

Research Scientist/ Senior Scientist/Principal Scientist – Protein Biochemist

Job Description

We are currently seeking a highly motivated and talented Protein Biochemist to support our R&D effort using our proprietary genetic engineered mice for antibody discovery. The primary job responsibilities include:

Lead design and build protein engineering pipeline using rational selection strategies to construct variants with desired biochemical and biophysical properties
Combine construct designs with cell-based assays, FACS and NGS for high-throughput screening of lead candidates
Execute protein expression, purification and biophysical characterization for internal pipeline advancement and external collaborations
Perform experiments, organize and analyze data, interpret results, record experiments in an electronic lab notebook, and summarize work in presentations and technical reports.
Assist in research design and experimental strategy to advance team goals
Maintain awareness of scientific and technical developments in the field of protein/antibody engineering
Collaborate with teams to maintain a safe and high-performing laboratory

Qualifications

PhD in biochemistry, molecular biology or related fields
Demonstrated mastery in understanding of protein structure and functional relationship
Experienced with protein expression systems in bacterial and mammalian platforms, purification techniques and protein biophysical characterization methods
Proven track record in problem solving, experimental design ability and cross team collaboration
NGS sequencing and phage/yeast display experience - a plus
Willing to learn and embrace new technologies to enhance team performance