Publications

  

1. Chen WV, Nwakeze CL, Denny CA, O’Keeffe S, Rieger MA, Mountoufaris G, Kirner A, Dougherty JD, Hen R, Wu Q, Maniatis T (2017) Pcdhac2 is required for axonal tiling and assembly of serotonergic circuitries in mice. Science 356: 406-411.


2. Mountoufaris G*, Chen WV*, Hirabayashi Y, O’Keeffe S, Chevee M, Nwakeze CL, Polleux F, Maniatis T (2017) Multi-cluster Pcdh diversity is required for mouse olfactory neural circuit assembly. Science 356: 411-414. *co-first author


3. Ye J, Beetz N, O'Keeffe S, Tapia JC, Macpherson L, Chen WV, Bassel-Duby R, Olson EN, Maniatis T (2015) hnRNP U protein is required for normal pre-mRNA splicing and postnatal heart development and function. Proc Natl Acad Sci U S A 112: E3020-29


4. Thu CA, Chen WV, Rubinstein R, Chevee M, Wolcott HN, Felsovalyi KO, Tapia JC, Shapiro L, Honig B, Maniatis T (2014) Single-cell identity generated by combinatorial homophilic interactions between a, b, and g protocadherins. Cell 158: 1045-1059


5. Chen WV, Maniatis T (2013) Clustered protocadherins. Development 140: 3297-3302


6. Chen WV, Alvarez FJ, Lefebvre JL, Friedman B, Nwakeze C, Geiman E, Smith C, Thu CA, Tapia JC, Tasic B, Sanes JR, Maniatis T (2012) Functional significance of isoform diversification in the protocadherin gamma gene cluster. Neuron 75: 402-409


7. Lefebvre JL, Kostadinov D, Chen WV, Maniatis T, Sanes JR (2012) Protocadherins mediate dendritic self-avoidance in the mammalian nervous system. Nature 488: 517-521


8. Li Y, Xiao H, Chiou TT, Jin H, Bonhomme B, Miralles CP, Pinal N, Ali R, Chen WV, Maniatis T, De Blas AL (2012) Molecular and functional interaction between protocadherin-gammaC5 and GABAA receptors. J Neurosci 32: 11780-11797


9. Kehayova P, Monahan K, Chen WV, Maniatis T (2011) Regulatory elements required for the activation and repression of the protocadherin-alpha gene cluster. Proc Natl Acad Sci U S A 108: 17195-17200


10. Chen WV, Delrow J, Corrin PD, Frazier JP, Soriano P (2004) Identification and validation of PDGF transcriptional targets by microarray-coupled gene-trap mutagenesis. Nat Genet 36: 304-312


11. Chen WV, Chen Z (2004) Differentiation trapping screen in live culture for genes expressed in cardiovascular lineages. Dev Dyn 229: 319-327


12. Chen WV, Soriano P (2003) Gene trap mutagenesis in embryonic stem cells. Methods Enzymol 365: 367-386

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